Table 3.
Crude Effect of Transcatheter Aortic Valve Replacement, Compared With Surgical Aortic Valve Replacement, on Hospital Complications, LOS, and Discharge Disposition in Hospitalizations of Octogenarians Undergoing Aortic Valve Replacement, Stratified by Charlson Comorbidity Index
| CCI <2 OR (95% CI) | CCI ≥2 OR (95% CI) | P Valuea | |
|---|---|---|---|
| In‐hospital complications | |||
| Permanent pacemaker implantation | 1.72 (1.25, 2.38) | 1.66 (1.23, 2.25) | 0.88 |
| Transient ischemic attack/stroke | 0.89 (0.52, 1.52) | 0.88 (0.57, 1.36) | 0.97 |
| Cardiogenic shock | 0.57 (0.29, 1.11) | 0.54 (0.35, 0.83) | 0.88 |
| Cardiac arrest | 1.03 (0.60, 1.75) | 1.68 (0.96, 2.96) | 0.22 |
| Acute kidney injury | 0.58 (0.43, 0.80) | 0.58 (0.48, 0.69) | 0.96 |
| Any bleeding | 0.49 (0.40, 0.59) | 0.42 (0.35, 0.50) | 0.25 |
| Blood transfusion | 0.28 (0.23, 0.35) | 0.37 (0.31, 0.44) | 0.06 |
| Vascular complications | 1.24 (0.82, 1.88) | 1.39 (0.95, 2.03) | 0.68 |
| Discharge disposition | |||
| Routine | 2.41 (2.01, 2.91) | 2.16 (1.83, 2.54) | 0.35 |
| Transfer, short‐term hospital | 0.35 (0.13, 0.96) | 0.81 (0.34, 1.92) | 0.26 |
| Transfer, skilled nursing facility | 0.41 (0.34, 0.49) | 0.45 (0.38, 0.53) | 0.43 |
| Death | 1.14 (0.62, 2.10) | 1.10 (0.69, 1.78) | 0.94 |
| CIE (95% CI) | CIE (95% CI) | P Valuea | |
|---|---|---|---|
| LOS after AVR, days | −2.61 (−2.99, −2.22) | −3.56 (−4.09, −3.04) | 0.004 |
AVR indicates aortic valve replacement; CCI, Charlson Comorbidity Index; CIE, change in estimate; LOS, length of stay; OR, odds ratio.
a
Testing the statistical significance of Charlson Comorbidity Index (<2 vs ≥2) as an interaction term for the association between TAVR and in‐hospital complication, discharge disposition, and LOS after AVR.