Table 6.
CNS Active Medications in Tox‐Positive SCAs (n=124)
| Type of Medication or Drug | Detected, N (%) | Therapeutic Levels, N (%) | Significant Levels, N (%) | Toxic Levels, N (%) |
|---|---|---|---|---|
| Illicit drugs | ||||
| Cocaine/benzyolecgonine (n=16) | 5 (31.3) | 1 (6.3) | 3 (18.7) | 7 (43.7) |
| Opioids (n=26) | 2 (7.7) | 10 (38.5) | 4 (15.3) | 10 (38.5) |
| Ethanol (n=50) | 3 (6.0) | 31 (62.0) | 13 (26.0) | 3 (6.0) |
| Psychotropic medications | ||||
| Selective serotonin reuptake inhibitors (n=18) | 10 (55.5) | 6 (33.3) | 1 (5.6) | 1 (5.6) |
| Serotonin and norepinephrine reuptake inhibitors (n=2) | 2 (100) | 0 (0) | 0 (0) | 0 (0) |
| Tricyclic antidepressants (n=8) | 0 (0) | 7 (87.5) | 0 (0) | 1 (12.5) |
| Benzodiazapines (n=16) | 11 (68.7) | 4 (25.0) | 1 (6.3) | 0 (0) |
| Dopamine antagonists (n=13) | 5 (38.5) | 6 (46.1) | 2 (15.4) | 0 (0) |
| Anticholinergics (n=6) | 1 (16.7) | 5 (83.3) | 0 (0) | 0 (0) |
| Other (n=8)a | 2 (25.0) | 3 (37.5) | 3 (37.5) | 0 (0) |
CNS indicates central nervous system; SCAs, sudden cardiac arrests.
a
Consists of domperidone, anticonvulsants, nonbenzodiazepine hypnotics, amphetamines such as dextroamphetamine, cyclobenzaprine, amantadine, and pregabalin.