Table 1.

Univariable and Multivariable analyses of clinic-pathologic parameters of overall survival in patient with GBM

		UVA			MVA
Parameter		HR	95% CI	P value	HR	95% CI	P value
Gender	Categorical	1.13	0.85–1.50	0.39	1.23	0.92–1.64	0.16
Age	Continuous	1.03	1.02–1.04	<0.001	1.00	0.99–1.02	0.23
KPS-70	< 70 vs 70 and above	0.55	0.40–0.76	<0.001	0.91	0.64–1.29	0.60
Treatment	None vs TMZ or IR alone	0.12	0.07–0.20	<0.001	0.12	0.070–0.21	<0.001
Treatment	None vs TMZ+IR (Stupp protocol)	0.03	0.02–0.05	<0.001	0.04	0.02–0.06	<0.001
miR-4516	Continuous	1.29	1.12–1.48	<0.001	1.49	1.12–1.99	0.01