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. 2019 Mar 29;10(25):2451–2461. doi: 10.18632/oncotarget.26789

Table 1A. Clinical characteristics for LNM patients with or without one or two bone metastase.

Timing for characteristics Clinical characteristics and treatments All patients (n = 45) Patients with LNM (n = 35) Patients with LNM and one or two bone metastases (n = 10)
Findings at diagnosis Age (years, median, IQR) 61 (57–66) 62 (58–69) 60 (51–64)
Gleason score 6 1 1 0
Gleason score 7 17 12 5
Gleason score 8 11 10 1
Gleason score 9 7 4 3
LNM 13 10 3
Initial treatment RP 29 20 9
RP with pelvic lymph node dissection 13 9 4
Radiotherapy 13 13 0
Adjuvant treatment Radiotherapy 13 13 0
Adjuvant or neoadjuvant ADT 10 8 2
Number of salvage treatments before LuPRLT (median, range) 2 (1–4) 2 (1–4) 3.5 (3–4)
Radiotherapy 10 4 6
Lymph node dissection 3 2 1
ADT 14 8 6
Docetaxel 12 7 5
Abiraterone 10 7 3
Enzalutamide 3 1 2
Findings at start of LuPRLT Age (years, median, IQR) 70 (64–75) 72 (65–75) 68 (63–72)
PSA (µg/l, median, IQR) 18.2 (3.3–39) 18.2 (2.3–39) 19.3 (4.1–49)

Abbreviations: ADT, androgen deprivation therapy; IQR, interquartile range; LNM, lymph node metastases; LuPRLT, 177Lu-prostate-specific membrane antigen radioligand therapy; RP, radical prostatectomy.