Table 2.
Distribution of Pseudomonas aeruginosa isolates from 18 patients according to phenotypic feature and genotype (pulsotype)
| Patient | No of Isolates | Mucoid/ Nonmucoid | Pigment | Genotype (Pulsotype) | No of isolates with the same genotype | Resistance or Intermediate Resistance to |
|---|---|---|---|---|---|---|
| 1 | 111 | Nm | - | - | - | OFX(R) |
| 112 | Nm | + | - | OFX(I) | ||
| 121 | Nm | + | - | |||
| 122 | Nm | - | - | |||
| 131 | Nm | - | - | |||
| 132 | M | - | - | |||
| 133 | Nm | - | - | |||
| 2 | 211 | M | + | 46* | 4 | - |
| 212 | Nm | + | 46* | OFX(IR) | ||
| 213 | Nm | + | 46* | - | ||
| 221 | M | + | 46* | - | ||
| 3 | 311 | Nm | - | 16 | 2 | - |
| 312 | Nm | - | 44 | - | ||
| 321 | M | - | 15 | OFX(R), CP(I) | ||
| 331 | Nm | + | 55 | - | ||
| 332 | Nm | + | 4* | PIP(I) | ||
| 333 | M | - | 4* | OFX(I) | ||
| 4 | 411 | Nm | + | 22 | 0 | TIM(I) |
| 421 | M | - | 15 | CAZ(R) | ||
| 422 | Nm | - | 25 | - | ||
| 431 | M | - | 27 | TZP(I), ATM(I), TIM(I) | ||
| 432 | Nm | - | 20 | CAZ(I), PIP(R), AN(R), GM(I), ATM(R), TIM(R) | ||
| 5 | 511 | M | - | 50 | 4 | AN(I), NET(I), GM(I), OFX(I) |
| 521 | M | - | 49* | CAZ(I), PIP(I), AN(R), NET(R), GM(R), TIM(I), NN(R) | ||
| 522 | NM | - | 49* | CAZ(R), PIP(I), AN(R), NET(I), GM(R), NN(I) | ||
| 531 | NM | - | 35 | AN(R), NET(R), GM(R), TIM(R), NN(R) | ||
| 532 | M | - | 30* | CAZ(I), AN(R), GM(R), NN(R) | ||
| 533 | NM | + | 30* | CAZ(R), PIP(R), AN(R), NET(R), GM(R), OFX(R), CP(I), TZP(I), TIM(I), NN(R) | ||
| 6 | 611 | NM | + | 1 | 3 | - |
| 612 | NM | - | 17 | MPM(R), IPM(I), CAZ(I), PIP(R), OFX(R), CP(I) | ||
| 621 | M | - | 42* | IPM(R) | ||
| 631 | M | - | 42* | IPM(R), PIP(I), OFX(I), TZP(I) | ||
| 632 | NM | - | 42* | OFX(R), CP(I) | ||
| 7 | 714 | NM | - | 3 | 4 | CAZ(I), PIP(R), AN(R), GM(R), OFX(I), TIM(I) |
| 721 | M | - | 14* | MPM(R), IPM(R), CAZ(R), PIP(R), OFX(R), CP(R), TZP(I), ATM(I), TIM(R) | ||
| 722 | M | - | 14* | MPM(R), IPM(R), AN(R), NET(R), GM(R), OFX(I), CP(I), NN(R) | ||
| 732 | M | - | 13* | - | ||
| 733 | NM | - | 13* | MPM(R), IPM(R), CAZ(R), PIP(R), AN(I), OFX(R), CP(I), TZP(R), ATM(I), TIM(R) | ||
| 8 | 811 | NM | - | 2 | 2 | - |
| 812 | M | - | 38 | AN(R), NET(I), GM(I), TIM(R) | ||
| 821 | M | - | 36 | M(I), OFX(I) | ||
| 822 | M | - | 37* | NET(I), TZP(I), TIM(R) | ||
| 832 | NM | - | 37* | AN(R), GM(I), OFX(I), CP(I) | ||
| 833 | M | - | 34 | CAZ(R), PIP(I), OFX(R), CP(I), TZP(I), ATM(R), TIM(R) | ||
| 9 | 911 | NM | - | 5 | 4 | - |
| 921 | M | - | 26* | - | ||
| 922 | NM | - | 26* | - | ||
| 931 | M | - | 26* | PIP(R), AN(R), NET(I), GM(R), OFX(I), TIM(I), NN(I) | ||
| 932 | M | - | 26* | AN(R), NET(R), GM(R), OFX(I), NN(R) | ||
| 10 | 1012 | NM | - | 8 | 0 | - |
| 1021 | NM | - | 21 | - | ||
| 11 | 1111 | M | - | 6 | 2 | CAZ(R), ATM(I), TIM(R) |
| 11 | 1112 | M | + | 11 | CAZ(R), OFX(I), ATM(I), TIM(I) | |
| 11 | 1113 | M | - | 9 | CAZ(R), PIP(I), ATM(I), TIM(I) | |
| 11 | 1121 | M | - | 21* | - | |
| 11 | 1122 | NM | + | 21* | - | |
| 11 | 1131 | M | - | 31 | TIM(I) | |
| 11 | 1132 | NM | - | 41 | PIP(I), AN(I), GM(R), OFX(R), CP(I) | |
| 12 | 1211 | NM | - | 47* | 4 | AN(I), GM(I) |
| 1212 | M | - | 47* | AN(I), GM(I) | ||
| 1213 | M | + | 48 | - | ||
| 1221 | M | - | 40* | AN(R), GM(I), NN(I) | ||
| 1222 | M | - | 54 | GM(I) | ||
| 1223 | NM | - | 40* | - | ||
| 1231 | M | + | 41 | AN(R), NET(R), GM(R), NN(I) | ||
| 1232 | M | + | 32 | GM(I) | ||
| 13 | 1311 | NM | - | 10 | 0 | CAZ(I), TIM(I) |
| 1313 | M | - | 32 | - | ||
| 1321 | M | - | 28 | MPM(I), IPM(R), CAZ(R), PIP(I), AN(I), OFX(I), TZP(I), ATM(R), TIM(R) | ||
| 1322 | NM | - | 53 | CIP(I), NN(R) | ||
| 1332 | NM | - | 45 | PIP(I), TZP(I), TIM(R) | ||
| 14 | 1411 | M | - | 43 | 5 | - |
| 1412 | NM | - | 25* | - | ||
| 1421 | M | - | 18* | - | ||
| 1422 | M | - | 25* | - | ||
| 1423 | NM | - | 25* | AN(R), NET(I), GM(R) | ||
| 1431 | M | - | 19 | AN(I) | ||
| 1432 | M | - | 32 | GM(I) | ||
| 1433 | NM | - | 18* | PIP(I), AN(I), GM(I), OFX(I) | ||
| 15 | 1511 | NM | + | 12* | 9 | PIP(I), AN(R), GM(R) |
| 1512 | M | - | 12* | AN(R), GM(I) | ||
| 1513 | M | - | 12* | - | ||
| 1521 | M | - | 12* | M(R) | ||
| 1522 | M | - | 12* | - | ||
| 1523 | NM | + | 12* | AN(R), NET(R), GM(R), NN(I) | ||
| 1531 | NM | - | 12* | CAZ(R), PIP(I), AN(R), NET(R), GM(R), NN(I) | ||
| 1532 | NM | - | 12* | MPM(R), IPM(R), PIP(R), ATM(I) | ||
| 1533 | M | - | 12* | MPM(R), IPM(R), PIP(R), AN(I), GM(R), OFX(I), TIM(I) | ||
| 16 | 1612 | M | - | 39 | 2 | TIM(I),ATM(I) |
| 1613 | M | - | 27 | TIM(I) | ||
| 1621 | NM | - | 33* | TIM(I) | ||
| 1622 | M | - | 28 | TIM(I) | ||
| 1632 | M | - | 33* | PIP(I), TZP(I), TIM(I), ATM(I) | ||
| 17 | 1711 | NM | + | 23* | 8 | AN(R), NET(R), GM(R), NN(R) |
| 1712 | M | - | 23* | - | ||
| 1713 | M | - | 23* | OFX(R), TIM(I) | ||
| 1714 | NM | + | 51 | AN(R), NET(R), GM(R), NN(R) | ||
| 1721 | M | - | 23* | - | ||
| 1722 | NM | - | 23* | OFX(R), TIM(R) | ||
| 1731 | NM | - | 24* | GM(I), OFX(R), TIM(I) | ||
| 1732 | NM | + | 24* | CAZ(R), PIP(I), AN(R), NET(R), GM(R), TIM(I) | ||
| 1733 | M | - | 24* | PIP(I) | ||
| 19 | 1911 | M | - | 39 | 2 | - |
| 1912 | M | - | 7 | - | ||
| 1921 | M | - | 52 | - | ||
| 1922 | M | - | 29* | - | ||
| 1931 | M | - | 29* | - |
Notes: Number of isolates are defined according to patient number, period of isolation, number of isolates in the mentioned period (eg, 213; 2 is patient number, 1 is period of isolation, 3 is the third isolate in the first period). *Persistent pulsotypes detected in each patient.
Abbreviations: M, mucoid; NM, nonmucoid; R, resistance; I, intermediate resistance; MPM, meropenem; IPM, imipenem; CAZ, ceftazidime; PIP, piperacillin; AN, amikacin; NET, netilmicin; GM, gentamicin; OFX, ofloxacin; CP, ciprofloxacin; TZP, piperacillin-tazobactam; ATM, aztreonam; TIM, ticarcillin-clavulanate; NN, tobramycine.