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. 2019 Apr 9;11:2831–2848. doi: 10.2147/CMAR.S183376

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© 2019 Tai et al.

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Celecoxib inhibited cell migration and invasion in Bel7402 cells. Compared with DMSO-treated Bel7402 cells, the migration rate (A–D) and invasion cells (E–H) were significantly inhibited by Celecoxib, EP2 inhibitor AH6809, Akt inhibitor MK2206, and ERK inhibitor AZD6244, but exacerbated by PGE2, which could be reversed by AH6809 (P<0.05). Scale bar =100 µm for wound-healing assay; scale bar =50 µm for transwell assay.