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. 2019 Apr 9;13:23–31. doi: 10.2147/BTT.S179006

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© 2019 Viscido et al.

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Trends in mortality and colectomy rate in different time periods. Mortality in acute severe ulcerative colitis (UC) in the pre-steroid era was up to 75%.¹²^,¹³ Steroids (1955) reduced mortality to 7%.¹⁴ Early surgery (1974) definitively reduced deaths to about 1%.¹⁷ The mortality rate of acute severe UC has remained unchanged at about 1% since 1974.⁴⁰ The need for colectomy was reduced by the introduction of rescue therapies.⁴⁴^,⁵².