Table 3.

The association between the germline variant rs61757955 and genomic and histological variables. Patients were divided based on whether or not they had the germline variant rs61757955. Patients with the germline variant rs61757955 were more likely to have CIC mutated gliomas and the 1p/19q co-deletion

Variable	Mean or Percentage (Wild Type)	Mean or Percentage (Mutant)	p-value
CIC Mutated	15.9%	38.1%	0.017
1p/19q Co-deletion	25.2%	47.6%	0.038
Oligodendroglioma	33.7%	42.9%	0.475
Total Somatic Mutation Count	30.9	30.0	0.766
Percent Aneuploidy	15.1%	11.7%	0.524
Astrocytoma	38.1%	42.9%	0.651
Grade 3	53.0%	42.9%	0.497
IDH Mutated	78.1%	85.7%	0.583
1p/19q Co-deletion	25.2%	47.6%	0.038
MGMT Promoter Methylation	77.8%	81.0%	1.000
Chr 7 Gain/Chr 10 Loss	13.0%	9.5%	1.000
Expression of GRB2 (FPKM)	45.7	44.4	0.636