Table 1.
Comparison of antepartum clinical features between women with postpartum abnormal glucose tolerance and normal glucose tolerance
| Abnormal glucose tolerance (n = 59) | Normal glucose tolerance (n = 154) | |
|---|---|---|
| Maternal age at delivery (years) | 39 (27–51) | 37 (23–46)* |
| Pregravid BMI (kg/m2) | 21.4 (17.0–33.9) | 21.6 (16.2–38.8) |
| Pregravid overweight | 18 (31) | 27 (17) |
| Nulliparous | 41 (69) | 87 (56) |
| Family history of diabetes | 19 (32) | 22 (14)** |
| GW at diagnosis of GDM (weeks) | 21 (9–33) | 16 (7–34) |
| GDM diagnosed before 20 weeks of pregnancy | 28 (47) | 84 (55) |
| Insulin use in pregnancy | 29 (49) | 54 (35) |
| Plasma glucose of the antepartum OGTT (mg/dL) | ||
| 0 min | 88 (76–109) | 92 (68–116)* |
| 30 min | 157 (107–211) | 153 (79–208) |
| 60 min | 182 (110–242) | 165 (88–272)*** |
| 120 min | 164 (112–230) | 147 (88–256)*** |
| Insulinogenic index | 0.56 (0.17–1.71) | 0.69 (0.02–7.53)** |
| ISOGTT | 2.69 (0.74–6.91) | 2.53 (0.54–7.27) |
| HOMA‐IR | 1.29 (0.39–6.57) | 1.49 (0.38–6.84) |
| ISSI‐2 | 0.80 (0.41–1.62) | 0.94 (0.36–2.51)*** |
| HbA1c at diagnosis of GDM (%) | 5.4 (4.8–6.1) | 5.3 (4.3–6.1) |
Data are median (range) or n (%). *P < 0.05, **P < 0.01, ***P < 0.001. BMI, body mass index; GDM, gestational diabetes mellitus; GW, gestational week; HbA1c, glycated hemoglobin; HOMA‐IR, homeostasis model assessment for insulin resistance; ISOGTT, insulin sensitivity index from the oral glucose tolerance test; ISSI‐2, Insulin Secretion‐Sensitivity Index‐2; OGTT, oral glucose tolerance test; overweight, body mass index ≥25 kg/m2.