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. 2018 Oct 13;10(3):602–612. doi: 10.1111/jdi.12931

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© 2018 The Authors. Journal of Diabetes Investigation published by Asian Association for the Study of Diabetes (AASD) and John Wiley & Sons Australia, Ltd

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Time‐dependent effects of docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) on the messenger ribonucleic acid levels of heme oxygenase‐1 (Ho‐1), nicotinamide adenine dinucleotide (phosphate) H quinone oxidoreductase 1 (Nqo1) and Catalase in immortalized mouse Schwann (IMS32) cells. IMS32 cells were cultured with (a,c,e) 7.5 μmol/L DHA or (b,d,f) 25 μmol/L EPA for the indicated times. Total ribonucleic acid was purified and quantified by real‐time reverse transcription polymerase chain reaction. Each value represents the mean ± standard error of three experiments. **P < 0.01 compared with each bovine serum albumin control. BSA, bovine serum albumin; Gaphd, glyceraldehyde 3‐phosphate dehydrogenase.