Table 3.

Correlation of serum 3‐carboxy‐4‐methyl‐5‐propyl‐2‐furanpropanoic acid levels with anthropometric parameters and biochemical indexes in 466 participants

	T2DM group n = 297		NGT group n = 169		Meta‐analysis		Heterogeneity tests
	B ± SE†	P‐value	B ± SE†	P‐value	B ± SE‡	P‐value	I 2 (%)
LDL‐c (mmol/L)	−0.120 ± 0.057	0.037	0.030 ± 0.063	0.632	−0.047 ± 0.075	0.527	67.92
HDL‐c (mmol/L)	−0.041 ± 0.017	0.015	−0.009 ± 0.027	0.725	−0.032 ± 0.014	0.027	0.59
TC (mmol/L)	−0.256 ± 0.076	0.001	0.088 ± 0.077	0.252	−0.089 ± 0.176	0.615	90.61
Triglycerides (mmol/L)§	−0.068 ± 0.039	0.082	−0.083 ± 0.041	0.046	−0.075 ± 0.028	0.008	0
SBP (mmHg)	−0.220 ± 1.312	0.867	2.210 ± 1.139	0.054	1.166 ± 0.086	0.175	48.88
DBP (mmHg)	−0.421 ± 0.723	0.561	1.454 ± 0.693	0.037	0.528 ± 0.937	0.573	71.47
GGT (U/L)§	−0.056 ± 0.045	0.210	−0.013 ± 0.050	0.794	−0.037 ± 0.033	0.272	0
ALT (U/L)§	−0.022 ± 0.033	0.508	−0.008 ± 0.041	0.851	−0.016 ± 0.026	0.521	0
AST (U/L)§	−0.050 ± 0.025	0.046	0.007 ± 0.025	0.786	−0.022 ± 0.018	0.224	61.53

^†The B ± standard error (SE) value shown indicates the association of 3‐carboxy‐4‐methyl‐5‐propyl‐2‐furanpropanoic acid with anthropometric parameters and biochemical indexes separately in the two groups by linear regression after adjustment for age, sex and body mass index. ^‡The B ± SE value shown represents the association of ‐carboxy‐4‐methyl‐5‐propyl‐2‐furanpropanoic acid with anthropometric parameters and biochemical indexes by combining the two groups with a fixed‐effects model for high‐density lipoprotein cholesterol (HDL‐c), triglyceride (TG), γ‐glutamyltransferase (GGT) and alanine aminotransferase (ALT), and a random‐effects model for low‐density lipoprotein cholesterol (LDL‐c), total cholesterol (TC), systolic blood pressure (SBP), diastolic blood pressure (DBP) and aspartate transaminase (AST). I ² was used to assess heterogeneity. ^§Log transformed before analysis.