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. 2019 May 2;9:6813. doi: 10.1038/s41598-019-43278-4

Table 7.

Risk of Hypertension in men according to plasma marker quartiles.

Plasma Marker Plasma markers
Quartile 1 Quartile 2 Quartile 3 Quartile 4
hs-CRP ≤0.55 0.56–1.04 1.05–2.07 ≥2.08
Model 1 1.000(ref.) 1.23(0.87–1.73) 1.66(1.17–2.36) 1.70(1.20–2.42)
Model 2 1.000(ref.) 1.12(0.79–1.59) 1.44(1.00–2.07) 1.41(0.98–2.04)
Model 3 1.000(ref.) 1.05(0.74–1.51) 1.36(0.94–1.96) 1.30(0.90–1.90)
Hcy ≤8.94 8.95–10.92 10.93–13.48 ≥13.49
Model 1 1.000(ref.) 1.11(0.79–1.56) 1.36(0.96–1.92) 2.03(1.42–2.90)
Model 2 1.000(ref.) 1.07(0.75–1.52) 1.37(0.96–1.96) 2.03(1.40–2.94)
Model 3 1.000(ref.) 1.02(0.71–1.45) 1.36(0.95–1.96) 2.00(1.37–2.92)
hs-TnT ≤6.48 6.49–8.95 8.96–11.72 ≥11.73
Model 1 1.000(ref.) 1.00(0.70–1.43) 1.16(0.80–1.66) 1.33(0.91–1.94)
Model 2 1.000(ref.) 1.06(0.74–1.53) 1.17(0.80–1.70) 1.36(0.92–2.00)
Model 3 1.000(ref.) 1.05(0.73–1.53) 1.09(0.75–1.60) 1.25(0.84–1.86)
NT-proBNP ≤26.08 26.09–43.50 43.51–76.49 ≥76.50
Model 1 1.000(ref.) 1.08(0.76–1.53) 1.08(0.76–1.54) 1.15(0.80–1.67)
Model 2 1.000(ref.) 1.10(0.77–1.57) 1.15(0.80–1.65) 1.33(0.91–1.95)
Model 3 1.000(ref.) 1.15(0.80–1.66) 1.23(0.85–1.77) 1.40(0.95–2.07)
25-OHD ≤12.04 12.05–16.50 16.51–22.69 ≥22.70
Model 1 1.000(ref.) 1.07(0.75–1.51) 1.33(0.94–1.90) 1.01(0.72–1.43)
Model 2 1.000(ref.) 1.10(0.77–1.57) 1.42(0.99–2.05) 1.09(0.76–1.56)
Model 3 1.000(ref.) 1.09(0.76–1.56) 1.40(0.97–2.02) 1.07(0.74–1.54)
HbA1c (%) ≤4.71 4.72–5.10 5.11–5.70 ≥5.71
Model 1 1.000(ref.) 1.14(0.81–1.60) 1.16(0.82–1.64) 1.96(1.37–2.81)
Model 2 1.000(ref.) 1.19(0.84–1.69) 1.17(0.82–1.67) 1.81(1.25–2.63)
Model 3 1.000(ref.) 1.09(0.76–1.56) 1.07(0.74–1.53) 1.77(1.15–2.73)
Model 4 1.000(ref.) 1.10(0.77–1.57) 1.01(0.70–1.46) 1.81(1.18–2.77)
SUA ≤303.36 303.37–353.11 353.12–403.82 ≥403.83
Model 1 1.000(ref.) 0.99(0.70–1.39) 1.11(0.79–1.58) 1.37(0.96–1.95)
Model 2 1.000(ref.) 0.92(0.65–1.31) 0.99(0.69–1.43) 1.12(0.77–1.64)
Model 3 1.000(ref.) 0.86(0.60–1.24) 0.93(0.64–1.34) 0.98(0.67–1.45)

*P < 0.05; P < 0.01;P < 0.001.

hs-CRP, high-sensitivity C-reactive protein; Hcy, Homocysteine; hs-cTnT, high-sensitivity cardiac troponin T; NT-proBNP, N-terminal prohormone of brain natriuretic peptide; 25OHD, 25-Hydroxyvitamin D; SUA, Serum uric acid; and HbA1c glycosylated hemoglobin A1c.

Model 1: Adjusted for age, cigarette status, Alcohol use, physical activity.

Model 2: Adjusted for the above plus total serum cholesterol, high-density lipoprotein, LDL-C, triglycerides, and creatinine

Model 3: Adjusted for the above plus BMI and Diabetes Mellitus.

Model 4: Sensitivity analysis for HBA1c.