Table 7.
Plasma Marker | Plasma markers | |||
---|---|---|---|---|
Quartile 1 | Quartile 2 | Quartile 3 | Quartile 4 | |
hs-CRP | ≤0.55 | 0.56–1.04 | 1.05–2.07 | ≥2.08 |
Model 1 | 1.000(ref.) | 1.23(0.87–1.73) | 1.66(1.17–2.36)† | 1.70(1.20–2.42)† |
Model 2 | 1.000(ref.) | 1.12(0.79–1.59) | 1.44(1.00–2.07) | 1.41(0.98–2.04) |
Model 3 | 1.000(ref.) | 1.05(0.74–1.51) | 1.36(0.94–1.96) | 1.30(0.90–1.90) |
Hcy | ≤8.94 | 8.95–10.92 | 10.93–13.48 | ≥13.49 |
Model 1 | 1.000(ref.) | 1.11(0.79–1.56) | 1.36(0.96–1.92) | 2.03(1.42–2.90)‡ |
Model 2 | 1.000(ref.) | 1.07(0.75–1.52) | 1.37(0.96–1.96) | 2.03(1.40–2.94)‡ |
Model 3 | 1.000(ref.) | 1.02(0.71–1.45) | 1.36(0.95–1.96) | 2.00(1.37–2.92)‡ |
hs-TnT | ≤6.48 | 6.49–8.95 | 8.96–11.72 | ≥11.73 |
Model 1 | 1.000(ref.) | 1.00(0.70–1.43) | 1.16(0.80–1.66) | 1.33(0.91–1.94) |
Model 2 | 1.000(ref.) | 1.06(0.74–1.53) | 1.17(0.80–1.70) | 1.36(0.92–2.00) |
Model 3 | 1.000(ref.) | 1.05(0.73–1.53) | 1.09(0.75–1.60) | 1.25(0.84–1.86) |
NT-proBNP | ≤26.08 | 26.09–43.50 | 43.51–76.49 | ≥76.50 |
Model 1 | 1.000(ref.) | 1.08(0.76–1.53) | 1.08(0.76–1.54) | 1.15(0.80–1.67) |
Model 2 | 1.000(ref.) | 1.10(0.77–1.57) | 1.15(0.80–1.65) | 1.33(0.91–1.95) |
Model 3 | 1.000(ref.) | 1.15(0.80–1.66) | 1.23(0.85–1.77) | 1.40(0.95–2.07) |
25-OHD | ≤12.04 | 12.05–16.50 | 16.51–22.69 | ≥22.70 |
Model 1 | 1.000(ref.) | 1.07(0.75–1.51) | 1.33(0.94–1.90) | 1.01(0.72–1.43) |
Model 2 | 1.000(ref.) | 1.10(0.77–1.57) | 1.42(0.99–2.05) | 1.09(0.76–1.56) |
Model 3 | 1.000(ref.) | 1.09(0.76–1.56) | 1.40(0.97–2.02) | 1.07(0.74–1.54) |
HbA1c (%) | ≤4.71 | 4.72–5.10 | 5.11–5.70 | ≥5.71 |
Model 1 | 1.000(ref.) | 1.14(0.81–1.60) | 1.16(0.82–1.64) | 1.96(1.37–2.81)† |
Model 2 | 1.000(ref.) | 1.19(0.84–1.69) | 1.17(0.82–1.67) | 1.81(1.25–2.63)† |
Model 3 | 1.000(ref.) | 1.09(0.76–1.56) | 1.07(0.74–1.53) | 1.77(1.15–2.73)† |
Model 4 | 1.000(ref.) | 1.10(0.77–1.57) | 1.01(0.70–1.46) | 1.81(1.18–2.77)† |
SUA | ≤303.36 | 303.37–353.11 | 353.12–403.82 | ≥403.83 |
Model 1 | 1.000(ref.) | 0.99(0.70–1.39) | 1.11(0.79–1.58) | 1.37(0.96–1.95) |
Model 2 | 1.000(ref.) | 0.92(0.65–1.31) | 0.99(0.69–1.43) | 1.12(0.77–1.64) |
Model 3 | 1.000(ref.) | 0.86(0.60–1.24) | 0.93(0.64–1.34) | 0.98(0.67–1.45) |
*P < 0.05; †P < 0.01;‡P < 0.001.
hs-CRP, high-sensitivity C-reactive protein; Hcy, Homocysteine; hs-cTnT, high-sensitivity cardiac troponin T; NT-proBNP, N-terminal prohormone of brain natriuretic peptide; 25OHD, 25-Hydroxyvitamin D; SUA, Serum uric acid; and HbA1c glycosylated hemoglobin A1c.
Model 1: Adjusted for age, cigarette status, Alcohol use, physical activity.
Model 2: Adjusted for the above plus total serum cholesterol, high-density lipoprotein, LDL-C, triglycerides, and creatinine
Model 3: Adjusted for the above plus BMI and Diabetes Mellitus.
Model 4: Sensitivity analysis for HBA1c.