Table 1.
Baseline characteristics of Crohn’s disease patients (CD) and healthy controls (HC).
| Variables | HC | CD | P-value |
|---|---|---|---|
| n = 27 | n = 51 | ||
| Plasma free thiols per gram of albumin (μmol/g) | 17.9 ± 1.8 | 14.7 ± 2.4 | < 0.001 |
| Age (years) | 51.2 ± 8.6 | 42.2 ± 12.2 | < 0.001 |
| Female, n (%) | 17 (63.0) | 38 (74.5) | 0.29 |
| BMI (kg/m2) | 26.4 ± 3.3 | 25.5 ± 5.3 | 0.32 |
| Current smoking, n (%) | 7 (25.9) | 6 (11.8) | 0.11 |
| Laboratory measurements | |||
| Hemoglobin (g/dL) | 14.5 ± 1.3 | 13.5 ± 1.3 | 0.001 |
| CRP (mg/L)∗ | 1.1 [0.6; 1.5] | 1.8 [0.6; 4.2] | 0.16 |
| ESR (mm/h)∗ | 3 [2; 4] | 14 [7; 27] | < 0.001 |
| WBC (× 109/L)∗ | 6.6 [5.0; 8.3] | 6.6 [5.4; 7.9] | 0.73 |
| Platelets (× 109/L)∗ | 239 [198; 303] | 290 [246; 321] | 0.02 |
| Albumin (g/L) | 45.6 ± 2.7 | 43.7 ± 2.7 | 0.003 |
| AST (U/L) | 20 ± 4 | 22 ± 8 | 0.18 |
| ALT (U/L)∗ | 20 [17; 21] | 20 [12; 23] | 0.89 |
| eGFR (mL/min × 1.73 m2) | 89 ± 12 | 100 ± 14 | < 0.001 |
| Creatinine (μmol/l) | 78.4 ± 15.8 | 69.7 ± 10.5 | 0.005 |
Data are presented as mean ± SD or proportions (n, %). ∗Skewed data are presented as median [interquartile range]. P-values were two-tailed and calculated using independent sample t-tests or Mann–Whitney U-tests, as appropriate. Significances are indicated in bold. CD, Crohn’s disease; HC, healthy controls; BMI, body mass index; CRP, C-reactive protein; ESR, erythrocyte sedimentation rate; WBC, white blood cell count; AST, aspartate transaminase; ALT, alanine transaminase; eGFR, estimated glomerular filtration rate.