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. 2019 Apr 18;11:3371–3379. doi: 10.2147/CMAR.S187233

Table 4.

Univariate and multivariate analysis for DFS

Characteristics Univariate Multivariate
p-Value HR 95%CI p-Value
Age (>50 vs ≤50) 0.069 0.485 0.237–0.989 0.047
Menopausal status (pre vs post) 0.765
Surgery (mastectomy vs BCS) 0.334
Pathology (IDC vs others) 0.799
Tumors (≤2 cm vs >2 cm) 0.252 1.365 0.643–2.897 0.417
Nodes involved (negative vs positive) 0.013 2.866 1.371–5.992 0.005
Grade (I-II vs III) 0.848
ER (positive vs negative) 0.557 0.725 0.351–1.495 0.383
PR (positive vs negative) 0.591 0.837 0.276–2.543 0.754
Ki67 (≤30% vs >30%) 0.013 0.404 0.185–0.885 0.023
Chemotherapy (EC-T vs others) 0.721
Radiation (yes vs no) 0.323
Endocrine therapy (yes vs no) 0.910
ALC (≥1.8 vs <1.8) 0.014 2.723 1.211–6.122 0.015
NLR (≥1.77 vs<1.77) 0.047 0.619 0.275–1.394 0.247
ANC (≥3.2 vs <3.2) 0.645

Abbreviations: IDC, invasive ductal carcinoma; BCS, breast conserving surgery; ER, estrogen receptor; PR, progestrone receptor; ANC, absolute neutrophil count; ALC, absolute lymphocyte count; NLR, neutrophil to lymphocyte ratio.