Table 2.
Univariate and multivariate analyses of overall survival in the training set
Variable | Univariate Analysis | Multivariate analysis | |
---|---|---|---|
P-Value | HR (95%CI) | P-Value | |
Age | <0.001 | ||
<45 | Reference | ||
≥45 | 2.706 (2.339–3.131) | <0.001 | |
Sex | <0.001 | ||
Female | Reference | ||
Male | 1.919 (1.681–2.192) | <0.001 | |
Race | 0.005 | ||
White | Reference | ||
Black | 1.471 (1.185–1.825) | 0.014 | |
Other | 0.849 (0.687–1.048) | 0.127 | |
Marital status | <0.001 | ||
Married | Reference | ||
Unmarried | 1.939 (1.709–2.199) | <0.001 | |
Tumor Size | <0.001 | ||
≤1.0 cm | Reference | ||
1.1–2.0 cm | 0.954 (0.799–1.139) | 0.603 | |
2.1–4.0 cm | 1.445 (1.080–1.934) | 0.013 | |
>4.0 cm | 2.787 (2.087–3.721) | <0.001 | |
Extrathyroidal extension | <0.001 | ||
Absent | Reference | ||
Present | 2.297 (1.665–3.170) | <0.001 | |
Multifocality | 0.685 | ||
Unifocal | |||
Multifocal | |||
Surgery | 0.521 | ||
Lobectomy | |||
Total thyroidectomy | |||
Radioactive iodine | <0.001 | ||
Yes | Reference | ||
No | 1.901 (1.669–2.167) | <0.001 | |
T stage | <0.001 | ||
T1 | Reference | ||
T2 | 0.706 (0.504–0.988) | 0.042 | |
T3 | 0.563 (0.390–0.814) | 0.002 | |
T4 | 1.418 (0.910–2.207) | 0.123 | |
N stage | <0.001 | ||
N0 | Reference | ||
N1 | 1.104 (0.945–1.289) | 0.214 | |
M stage | <0.001 | ||
M0 | Reference | ||
M1 | 6.374 (5.054–8.038) | <0.001 |