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. 2019 Apr 24;11:3535–3544. doi: 10.2147/CMAR.S194366

Table 2.

Univariate and multivariate analyses of overall survival in the training set

Variable Univariate Analysis Multivariate analysis
P-Value HR (95%CI) P-Value
Age <0.001
 <45 Reference
 ≥45 2.706 (2.339–3.131) <0.001
Sex <0.001
 Female Reference
 Male 1.919 (1.681–2.192) <0.001
Race 0.005
 White Reference
 Black 1.471 (1.185–1.825) 0.014
 Other 0.849 (0.687–1.048) 0.127
Marital status <0.001
 Married Reference
 Unmarried 1.939 (1.709–2.199) <0.001
Tumor Size <0.001
 ≤1.0 cm Reference
 1.1–2.0 cm 0.954 (0.799–1.139) 0.603
 2.1–4.0 cm 1.445 (1.080–1.934) 0.013
 >4.0 cm 2.787 (2.087–3.721) <0.001
Extrathyroidal extension <0.001
 Absent Reference
 Present 2.297 (1.665–3.170) <0.001
Multifocality 0.685
 Unifocal
 Multifocal
Surgery 0.521
 Lobectomy
 Total thyroidectomy
Radioactive iodine <0.001
 Yes Reference
 No 1.901 (1.669–2.167) <0.001
T stage <0.001
 T1 Reference
 T2 0.706 (0.504–0.988) 0.042
 T3 0.563 (0.390–0.814) 0.002
 T4 1.418 (0.910–2.207) 0.123
N stage <0.001
 N0 Reference
 N1 1.104 (0.945–1.289) 0.214
M stage <0.001
 M0 Reference
 M1 6.374 (5.054–8.038) <0.001