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. 2019 Apr 24;11:3535–3544. doi: 10.2147/CMAR.S194366

Table 3.

Univariate and multivariate analyses of cancer-specific survival in the training set

Variable Univariate analysis Multivariate analysis
P-value HR (95%CI) P-value
Age <0.001
 <45 Reference
 ≥45 3.702 (2.667–5.139) <0.001
Sex <0.001
 Female Reference
 Male 1.542 (1.2058–1.972) <0.001
Race 0.018
 White Reference
 Black 1.291 (0.790–2.109) 0.309
 Other 1.213 (0.881–1.668) 0.236
Marital status 0.008
 Married Reference
 Unmarried 1.423 (1.116–1.816) 0.004
Tumor Size <0.001
 ≤1.0 cm Reference
 1.1–2.0 cm 1.272 (0.773–2.094) 0.343
 2.1–4.0 cm 2.240 (1.295–3.874) 0.004
 >4.0 cm 4.351 (2.521–7.507) <0.001
Extrathyroidal extension <0.001
 Absent Reference
 Present 2.017 (1.209–3.365) 0.007
Multifocality 0.506
 Unifocal
 Multifocal
Surgery 0.191
 Lobectomy
 Total thyroidectomy
Radioactive iodine 0.925
 Yes
 No
T stage <0.001
 T1 Reference
 T2 1.143 (0.582–2.246) 0.698
 T3 1.808 (0.935–3.497) 0.079
 T4 7.009 (3.312–14.834) <0.001
N stage <0.001
 N0 Reference
 N1 1.643 (1.253–2.153) <0.001
M stage <0.001
 M0 Reference
 M1 8.462 (6.334–11.307) <0.001