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. 2019 Apr 2;11:2565–2578. doi: 10.2147/CMAR.S190332

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© 2019 Hao et al.

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NECTIN4 is upregulated in PTC.

Notes: (A) The expression of NECTIN4 was significantly upregulated in the PTC samples in the our cohort (Figure 1B, P<0.0001). (B) The expression of NECTIN4 was significantly upregulated in the PTC samples in the TCGA cohort. (Figure 1C, P<0.001). (C) The relative expression of NECTIN4 (compared with the GAPDH gene) was examined via RT-qPCR. Compared to normal thyroid cell lines,TPC-1 and KTC cell lines have higher NECTIN4 expression while BCPAP has lower expression. *P<0.05, ***P<0.001 in comparison with Si-NC or GAPDH using student’s t-test.

Abbreviations: PCT, papillary thyroid cancer; RT-qPCR, reverse transcription—quantitative PCR; TCGA, The Cancer Genome Atlas.