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NECTIN4 gene knockdown induces the cell apoptosis of PTC cell lines in vitro.
Notes: (A and B) Annexin V/PI assay was applied to analyze the TPC1 and KTC-1 cell lines transfected with Si-NC or Si-RNA1 or Si-RNA2. Knocking down NECTIN4 could increase apoptotic cell death in thyroid cancer cells. The columns represent the mean of death cell numbers from at least three independent experiments. *P<0.05, **P<0.01 and ***P<0.001 in comparison with si-NC using Student’s t-test.
