Table 1.

Association between NECTIN4 expression and clinicopathological features in the TCGA cohort

Clinicopathological features	Low expression (N=251)	High expression (N=251)	P-value
Gender			0.545
Female	181	187
Male	70	64
Age (years)			0.178
Median (P25–P75)	46 (34–59)	52 (41–63)
<45	120	105
≥45	131	146
Histological type			<0.001*
Classical	154	203
Other types	97	48
Multi-nodularity			0.588
Yes	110	116
No	137	131
Tumor size (mm)			0.017
≥20	167	191
<20	83	59
Lymph-node metastasis			<0.001*
Yes	79	145
No	141	87
Distant metastasis			0.588
Yes	6	8
No	245	243
Disease stage (AJCC7)			<0.001*
I+II	194	139
III+IV	57	107

Notes: *Chi-square test, p-value<0.05.

Abbreviations: AJCC, American Joint Committee on Cancer; TCGA, The Cancer Genome Atlas.