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. 2019 Apr 10;12:2703–2712. doi: 10.2147/OTT.S201664

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© 2019 Ouyang et al.

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IL-37 induced the apoptosis of cervical cancer cells which involved Bim. (A) The apoptosis rate of HeLa cells transfected with control plasmid. (B) The apoptosis rate of HeLa cells transfected with IL-37 gene. (C) The apoptosis rate of HeLa cells transfected with SiBim. (D) The apoptosis rate of HeLa cells cotransfected with IL-37 gene and SiBim. (E) The apoptosis rates in the four groups in HeLa. (F) The apoptosis rate of C33A cells transfected with control plasmid. (G) The apoptosis rate of C33A cells transfected with IL-37 gene. (H) The apoptosis rate of C33A cells transfected with SiBim. (I) The apoptosis rate of C33A cells cotransfected with IL-37 gene and SiBim. (J) The apoptosis rates in the four groups in C33A. HeLa-NC: HeLa cells transfected with control plasmid; HeLa-IL-37: HeLa cells transfected with IL-37 gene; HeLa-SiBim: HeLa cells transfected with SiBim; HeLa-IL-37+ SiBim: HeLa cells transfected with IL-37 gene and SiBim. C33A-NC: C33A cells transfected with control plasmid; C33A-IL-37: C33A cells transfected with IL-37 gene; C33A-SiBim: C33A cells transfected with SiBim; C33A-IL-37+ SiBim: C33A cells transfected with IL37 gene and SiBim.*P<0.05 and **P<0.01.