Table 3.
Univariate and multivariate survival analysis of patients with colorectal cancer
| Factors | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| HR (95%CI) | P-value | HR (95%CI) | P-value | |
| Age (years) | ||||
| ≤65 vs >65 | 1.16 (0.62–2.16) | 0.6703 | — | — | 
| Gender | ||||
| Male vs female | 1.59 (0.84–3.00) | 0.2282 | — | — | 
| Histology type | ||||
| Well, moderate vs poor | 0.94 (0.43–2.06) | 0.7700 | — | — | 
| Clinical stages (TNM) | ||||
| I, II vs III, IV | 0.51 (0.30–0.88) | 0.0140 | 0.45 (0.23–0.89) | 0.021 | 
| Tumor location | ||||
| Colon vs rectal | 1.01 (0.55–1.87) | 0.2936 | — | — | 
| SIK1 expression | ||||
| High vs low | 0.32 (0.17–0.60) | <0.001 | 0.33 (0.16–0.67) | 0.002 |