Table 5.

SAXS parameters for data validation and interpretation

Protein sample	Rga	Rgb	Dmaxc	Massd	Masse
	Å	Å (real)	Å	kDa	kDa
HTT/HAP40	63.3 + 2.1	57.7 + 0.4	179	386 (390)	391
HTT	69.9 + 2.2	67.7 + 0.8	220	422 (350)	428

^a Radius of gyration (R_g) was calculated the using Guinier fit in the q range 0.015 < q < 0.025 Å⁻¹ and 0.012< q < 0.019 Å⁻¹ for HTT/HAP40 and HTT, respectively.

^b Radius of gyration was calculated using GNOM.

^c Maximum distance between atoms was calculated using GNOM.

^d Molecular mass was estimated using SAXSMoW (47). The mass expected from the sequence is shown in the parentheses.

^e Molecular mass was estimated from SAXS data based on volume of correlation (Vc) (48).