Table 3.
Secondary perinatal outcomes
| Revealed PlGF (intervention; n=573) | Concealed PlGF (n=446) | ||
|---|---|---|---|
| Gestation at delivery, weeks | 36·6 (3·0) | 36·8 (3·0) | |
| Vital status at birth | |||
| Livebirth | 567 (99%) | 440 (99%) | |
| Intrauterine fetal death | 7 (1%) | 6 (1%) | |
| Perinatal adverse outcomes* | 86 (15%) | 63 (14%) | |
| Composite perinatal adverse outcome components | |||
| Any grade of intraventricular haemorrhage | 7 (1%) | 11 (3%) | |
| Seizure | 0 | 2 (<1%) | |
| Any grade of retinopathy of prematurity | 9 (2%) | 9 (2%) | |
| Respiratory distress syndrome | 78 (14%) | 54 (12%) | |
| Bronchopulmonary dysplasia | 5 (1%) | 3 (1%) | |
| Necrotising enterocolitis (stage 2 or 3) | 7 (1%) | 7 (2%) | |
| Perinatal deaths | 6 (1%) | 4 (1%) | |
| Late neonatal deaths (8–27 complete days of life) | 3 (1%) | 1 (<1%) | |
| Neonatal unit admission | 195 (34%) | 146 (33%) | |
| Birthweight, g | 2657 (887) | 2720 (858) | |
| Birthweight centile | 42·8 (33·0) | 43·4 (33·1) | |
| Apgar score at 5 min after delivery | 9·14 (1·52) | 9·24 (1·41) | |
| Umbilical arterial pH at birth | 7·25 (0·11) | 7·23 (0·09) | |
| Umbilical arterial pH <7·2 at birth | 141 (25%) | 135 (30%) | |
| Perinatal health resource use (in those admitted) | |||
| Inpatient nights in the neonatal unit | 22·1 (25·9) | 24·6 (35·2) | |
| Nights in the intensive care or high-dependency units | 15·2 (1·7) | 24·2 (3·8) | |
| Nights in the special care baby unit | 14·7 (14·4) | 13·09 (12·6) | |
Data are mean (SD), n (%), or median (IQR). Fetuses could have one or several composite perinatal adverse components. PlGF=placental growth factor.
*
Only components with an outcome are included here; full details are shown in the appendix.