Figure 1.

Mean alcohol intake in men from ten study areas in China, subdivided by nine possible genotypes of two common variants that alter alcohol metabolism

For each genotype, the A allele discourages alcohol consumption. Within each area, mean alcohol intake was plotted according to the nine possible ALDH2-rs671 and ADH1B-rs1229984 genotypes (each AA, AG, or GG) from AA/AA homozygosity for both variants to GG/GG homozygosity for both variants. Alcohol intake thresholds were defined at 10, 25, 50, 100, and 150 g per week to assign individuals into six categories of mean male alcohol intake on the basis of their genotype and area.