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. 2019 Apr 26;57(5):e01794-18. doi: 10.1128/JCM.01794-18

TABLE 2.

TypeSeq and Linear Array test concordance on 849 clinical specimens for 37 HPV genotypes detectable by both assays

HPV genotype No. of specimens
% Prevalence
% Agreement
TS−/LA−d TS+/LA− TS−/LA+ TS+/LA+ TS LA Total Positive McNemar P value
6 757 10 10 72 9.7 9.7 97.6 78.3 0.82
11 820 0 3 26 3.1 3.4 99.7 89.7 0.25
16 534 11 16 288 35.2 35.8 96.8 91.4 0.44
18 739 11 5 94 12.4 11.7 98.1 85.5 0.21
26 835 1 1 12 1.5 1.5 99.8 85.7 0.48
31 722 18 4 105 14.5 12.8 97.4 82.7 0.005
33 796 4 0 49 6.2 5.8 99.5 92.5 0.13
34 834 8 0 7 1.8 0.8 99.1 46.7 0.013
35 762 11 3 73 9.9 9.0 98.4 83.9 0.061
39 736 6 9 98 12.3 12.6 98.2 86.7 0.61
40 791 14 3 41 6.5 5.2 98.0 70.7 0.015
42 735 22 6 86 12.7 10.8 96.7 75.4 0.005
44 787 6 7 49 6.5 6.6 98.5 79.0 1
45 756 8 7 78 10.1 10.0 98.2 83.9 1
51 697 18 28 106 14.6 15.8 94.6 69.7 0.18
52 697 46 9 97 16.8 12.5 93.5 63.8 NEe
53 709 9 12 119 15.1 15.4 97.5 85.0 0.66
54 767 6 17 59 7.7 9.0 97.3 72.0 0.037
56 736 20 8 85 12.4 11.0 96.7 75.2 0.037
58 758 19 1 71 10.6 8.5 97.6 78.0 0.0001
59 722 9 10 108 13.8 13.9 97.8 85.0 1
61 759 9 12 69 9.2 9.5 97.5 76.7 0.66
62 728 6 25 90 11.3 13.6 96.4 74.4 0.001
66 729 14 16 90 12.3 12.5 96.5 75.0 0.85
67 768 36 1 44 9.4 5.3 95.6 54.3 NE
68a 772 6 6 65 8.4 8.4 98.6 84.4 0.77
69 838 0 1 10 1.2 1.3 99.9 90.9 1
70 800 2 14 33 4.1 5.5 98.1 67.4 0.006
71 840 1 1 7 0.9 0.9 99.8 77.8 0.48
72 812 4 2 31 4.1 3.9 99.3 83.8 0.68
73 787 0 13 49 5.8 7.3 98.5 79.0 0.0009
81 794 2 8 45 5.5 6.2 98.8 81.8 0.11
82b 779 6 4 60 7.8 7.5 98.8 85.7 0.75
83 789 2 34 24 3.1 6.8 95.8 40.0 NE
84 748 10 29 62 8.5 10.7 95.4 61.4 0.004
89 741 18 17 73 10.7 10.6 95.9 67.6 1
HRc 76 19 24 730 88.2 88.8 94.9 94.4 0.54
a

HPV68 represents results for the lineages detectable by LA (C to F, formerly “68b”).

b

HPV82 represents a combined result for 82 and 82v (IS39).

c

HR represents HPV types 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, and 68.

d

TS, TypeSeq; LA, Linear Array.

e

NE, not evaluable.