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. 2019 Apr 26;57(5):e01664-18. doi: 10.1128/JCM.01664-18

TABLE 4.

Antimicrobial resistance of E. coli isolates of ST1193-H64, its main pulsotypes (PFGEs), and other STc14 STs

Antimicrobial agenta Prevalence of resistance by ST1193-H64 status within STc14 (% within column)
 2-Group P valued Prevalence of resistance by pulsotype within ST1193-H64 (% within column)
 3-Group P valued
Other STc14 isolates (n = 29) ST1193-H64 (n = 117b or 77c) PFGE 1297 (n = 55b or 31c) PFGE 1298 (n = 17b or 16c) PFGE 2123 (n = 23b or 9c)
Penicillin
    AMP 56 83 0.01 71f 100e 96 0.004
    SAM 45 33 0.28 29 24 57f 0.04
    PRL 52 79 0.008 61f 100e 89 0.008
Cephalosporin
    KZ 21 56 0.001 40g 94g 39 <0.001
Aminoglycoside
    GEN 0 21 0.004 11f 77g 0f <0.001
    STR 21 81 <0.001 65f 88 100 0.04
    AMK 0 7 0.32 0 19 0 0.02
Folate inhibitor
    TMP 3 68 <0.001 58 88 100e 0.007
    SXT 45 63 0.09 49f 82 93g <0.001
Quinolone
    NA 10 99 <0.001 100 100 89 0.07
    CIP 0 100 <0.001 100 100 100 1.0
Tetracycline
    TE 10 61 <0.001 42f 88e 100f <0.001
a

AMK, amikacin; AMP, ampicillin; CIP, ciprofloxacin; GEN, gentamicin; KZ, cefazolin; NA, nalidixic acid; PRL, piperacillin; SAM, ampicillin-sulbactam; STR, streptomycin; SXT, trimethoprim-sulfamethoxazole; TE, tetracycline; TMP, trimethoprim. The antimicrobial classes and agents shown are those for which resistance was significantly clonally distributed. Additional studied agents, for which resistance was not significantly clonally distributed, included (range of resistance prevalence by clonal subset) piperacillin-tazobactam (TZP) (0% to 22%), ceftriaxone (CRO) (0% to 18%), ceftazidime (CAZ) (0% to 6%), ertapenem (ETP) (0% to 1%), imipenem (IMP) (0% to 3%), aztreonam (ATM) (0% to 10%), nitrofurantoin (NF) (0% to 12%), and chloramphenicol (C) (0% to 13%).

b

A larger set of ST1193-H64 isolates was tested against only AMP, CAZ, CRO, ETP, GEN, IMP, KZ, NF, SAM, and SXT.

c

A smaller set of ST1193-H64 isolates was also tested against AMK, ATM, C, NA, PRL, STR, TE, TMP, and TZP.

d

Two-group P values (by Fisher’s exact test, two-tailed) and 3-group P values (by 3-group Pearson χ2) are shown in boldface; P < 0.05.

e

P < 0.05 (Fisher’s exact test, two-tailed) for comparisons of each pulsotype versus all other ST1193 isolates.

f

P ≤ 0.01 (Fisher’s exact test, two-tailed) for comparisons of each pulsotype versus all other ST1193 isolates.

g

P ≤ 0.001 (Fisher’s exact test, two-tailed) for comparisons of each pulsotype versus all other ST1193 isolates.