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pH sensitivity to dissociation of mutant FMDV empty capsids containing the D3195N, A2065H, or H3141A substitutions relative to that of the wt empty capsid control. The percentages of intact capsids remaining after different incubation times in a representative experiment at pH 5.0 and 25°C are indicated in each case. For each mutant, the average value obtained from 2 independent experiments and the corresponding error bar (standard deviation) are indicated.
