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Effect of the candidate novel antiviral factors on PRRSV replication. (A) List of candidate genes for screening of novel anti-PRRSV factors. (B) Western blot of transfected Marc-145 cells challenged with PRRSV for 30 h. (C) Cell viability assay on cells overexpressing the candidate antiviral genes. (D) Western blot of ZAP-L (long isoform of ZAP)- and ZAP-transfected Marc-145 cells challenged with PRRSV for 30 h. The data presented are means ± SD from three independent experiments.
