FIG 6.

Comparison of the recruitment of DNA-PKcs and E4orf4 to virus replication centers. (A) HeLa cells were infected with WT-Ad5 and fixed at various times postinfection. One set of cells was stained with DBP and E4orf4 antibodies, while another set was stained with DBP and DNA-PKcs antibodies. Representative images are shown for each time point. (B) HeLa cells were infected with phenotypically WT-Ad5 (dl309) or a mutant Ad lacking E4orf4 (dl358) and processed as described above for panel A. hpi, hours postinfection.