TABLE 1.
Mutant | ID | Predicted function | Class |
---|---|---|---|
1 | BOW65_RS02945 | Pyridoxalphosphate-dependent aminotransferase | Secondary metabolite production |
2 | BOW65_RS02935 | 3-Oxoacyl-ACP synthase | Secondary metabolite production |
3, 4 | BOW65_RS24575 | Two-component sensor histidine kinase CbrA | Cell signaling and transcription regulation |
5, 6 | BOW65_RS20110 | CysB family transcriptional regulator | Cell signaling and transcription regulation |
7 | BOW65_RS21410 | Multisensor hybrid histidine kinase | Cell signaling and transcription regulation |
8 | BOW65_RS06475 | Outer membrane protein assembly factor BamC | Cell surface |
9 | BOW65_RS22455 | Peptidoglycan-associated lipoprotein | Cell surface |
10 | BOW65_RS29255 | Phospholipid/glycerol acyltransferase | Cell surface |
11 | BOW65_RS28295 | Acetylglutamate kinase | Metabolism |
12 | BOW65_RS08620 | Methylcitrate synthase | Metabolism |
13 | BOW65_RS24475 | Ketol-acid reductoisomerase | Metabolism |
14 | BOW65_RS07790 | Succinyl-CoA synthetase subunit alpha | Metabolism |
15 | BOW65_RS08625 | 2-Methylisocitrate dehydratase | Metabolism |
16a | BOW65_RS24600 | 3-Methyl-2-oxobutanoate hydroxymethyltransferase | Metabolism |
16a | BOW65_RS24605 | Pantoate-beta-alanine ligase | Metabolism |
Transposon insertion in the promoter 5′ region of an operon conformed for these two genes.