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. 2019 Apr 26;10:453. doi: 10.3389/fphar.2019.00453

Table 1.

Intrinsic electrogenic properties of small-sized DRG neurons of Sham + Veh, CPIP + Veh, and CPIP + AMG9810 groups of rats.

Sham + Veh CPIP + Veh CPIP + AMG9810



Mean SEM n Mean SEM n Mean SEM n
Input resistance (MΩ) 564.1 40.6 26 537.9 18.2 33 521.7 33.6 33
Capacitance (pF) 30.1 0.4 30 30.3 0.5 31 29.5 0.4 31
RMP (mV) -65.8 0.9 27 -66.9 1.1 31 -64.9 0.8 32
AP amplitude (mV) 118.5 1.8 32 119.0 2.7 30 120.7 2.2 30
AHP amplitude (mV) 25.1 1.2 32 25.5 0.5 26 24.2 0.9 31
AP frequency (spikes/s, step protocol) 0.9 0.1 30 2.4* 0.4 30 1.3# 0.2 30
AP frequency (spikes/s, ramp protocol) 2.1 0.2 31 5.1** 0.4 30 2.7## 0.3 30
Threshold (pA, step protocol) 439.5 21.6 37 249.0** 8.1 32 352.9## 20.8 32
Threshold (pA, ramp protocol) 726.6 20.5 30 424.4** 23.3 31 529.5## 33.9 30

AP, action potential; AHP, after hyperpolarization.

p < 0.05, ∗∗p < 0.01, compared with sham group; #p < 0.05, ##p < 0.01, compared with CPIP + Veh group.