Fig. 2.
Mab 10C4–8E7 specifically inhibits Len/17-MDV growth in MDCK cells. (A) Cells were infected with 10 MOI of Len/17-MDV and cultured in the presence of indicated dose of 10C4–8E7 mAb. (B) Cells were infected with LV4A (H3N2), LV14A (H1N1pdm09) or LV15A (H3N2) at MOI of 10 and cultured with 5 μg/ml of 10C4–8E7 mAb or without mAb (control) for 3 days. The virus titers were determined by TCID50 assay in MDCK cells. Statistically significant differences from the control are indicated with asterisks, **P < 0.01, *P < 0.05 (Student t-test). The average titer ± SD from three independents experiments is shown.