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. Author manuscript; available in PMC: 2019 May 3.
Published in final edited form as: Infect Control Hosp Epidemiol. 2015 Oct 21;37(1):19–25. doi: 10.1017/ice.2015.252

TABLE 2.

Predictors of Healthcare Facility-Onset Clostridium difficile Infection (CDI) Events by Univariate and Multivariate Analyses among Inpatient Acute Care Hospitals Reporting Laboratory-Identified Events to the National Healthcare Safety Network, 2012

Univariate
Multivariate
Parameter Est. Rate Ratio (95% CI) P Value Est. Rate Ratio (95% CI) P Value
CDI prevalence rate, per 0.1 unit increase 0.146 1.157 (1.143–1.172) <.0001 0.138 1.148 (1.134–1.162) <.0001
Case mix index, per 0.1 unit increase 0.062 1.064 (1.049–1.079) <.0001 0.033 1.034 (1.021–1.047) <.0001
CDI test type
 NAAT vs. EIA/Othera 0.497 1.643 (1.536–1.758) <.0001 0.211 1.235 (1.163–1.312) <.0001
Hospital size, No. beds <.0001b <.0001b
 ≥254 vs <120a 0.382 1.466 (1.340–1.603) <.0001 0.204 1.227 (1.127–1.335) <.0001
 120–253 vs <120a 0.192 1.211 (1.105–1.328) <.0001 0.113 1.119 (1.035–1.210)  .0047
Medical school affiliation: <.0001b  .0115b
 Major vs undergraduate/Non-teachinga 0.199 1.221 (1.110–1.342) <.0001 0.110 1.117 (1.033–1.207) .0054
 Graduate vs undergraduate/Non-teachinga 0.102 1.107 (1.009–1.214)  .0308 0.069 1.071 (0.997–1.151) .0597

NOTE. NAAT, nucleic acid amplification test; EIA, enzyme immunoassay.

a

Referent group.

b

Main effect P value.