TABLE 2.
Predictors of Healthcare Facility-Onset Clostridium difficile Infection (CDI) Events by Univariate and Multivariate Analyses among Inpatient Acute Care Hospitals Reporting Laboratory-Identified Events to the National Healthcare Safety Network, 2012
| Univariate |
Multivariate |
|||||
|---|---|---|---|---|---|---|
| Parameter | Est. | Rate Ratio (95% CI) | P Value | Est. | Rate Ratio (95% CI) | P Value |
| CDI prevalence rate, per 0.1 unit increase | 0.146 | 1.157 (1.143–1.172) | <.0001 | 0.138 | 1.148 (1.134–1.162) | <.0001 |
| Case mix index, per 0.1 unit increase | 0.062 | 1.064 (1.049–1.079) | <.0001 | 0.033 | 1.034 (1.021–1.047) | <.0001 |
| CDI test type | ||||||
| NAAT vs. EIA/Othera | 0.497 | 1.643 (1.536–1.758) | <.0001 | 0.211 | 1.235 (1.163–1.312) | <.0001 |
| Hospital size, No. beds | … | <.0001b | … | <.0001b | ||
| ≥254 vs <120a | 0.382 | 1.466 (1.340–1.603) | <.0001 | 0.204 | 1.227 (1.127–1.335) | <.0001 |
| 120–253 vs <120a | 0.192 | 1.211 (1.105–1.328) | <.0001 | 0.113 | 1.119 (1.035–1.210) | .0047 |
| Medical school affiliation: | … | <.0001b | … | .0115b | ||
| Major vs undergraduate/Non-teachinga | 0.199 | 1.221 (1.110–1.342) | <.0001 | 0.110 | 1.117 (1.033–1.207) | .0054 |
| Graduate vs undergraduate/Non-teachinga | 0.102 | 1.107 (1.009–1.214) | .0308 | 0.069 | 1.071 (0.997–1.151) | .0597 |
NOTE. NAAT, nucleic acid amplification test; EIA, enzyme immunoassay.
Referent group.
Main effect P value.