TABLE 3.
aORs with 95% CIs for DQI and MDS quartiles for all gastroschisis cases and stratified by maternal race/ethnicity, NBDPS,1997–20091
| DQI | MDS | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | P-trend2 | 1 | 2 | 3 | 4 | P-trend2 | |
| All | ||||||||||
| Controls, n | 2577 | 2269 | 2307 | 2330 | 2421 | 2492 | 2300 | 2270 | ||
| Cases, n | 373 | 264 | 236 | 252 | 384 | 313 | 232 | 196 | ||
| aOR3 (95% CI) | ref | 0.88 (0.73, 1.06) | 0.79 (0.64, 0.96) | 0.81 (0.64, 1.02) | 0.03 | ref | 0.96 (0.81, 1.15) | 0.85 (0.70, 1.04) | 0.78 (0.62, 0.97) | 0.014 |
| NH whites | ||||||||||
| Controls, n | 1806 | 1491 | 1335 | 971 | 1846 | 1699 | 1279 | 779 | ||
| Cases, n | 225 | 140 | 116 | 98 | 278 | 156 | 96 | 49 | ||
| aOR4 (95% CI) | ref | 0.99 (0.77, 1.27) | 0.90 (0.68, 1.18) | 1.07 (0.77, 1.48) | 0.93 | ref | 0.82 (0.65, 1.02) | 0.86 (0.66, 1.12) | 0.85 (0.60, 1.20) | 0.17 |
| Hispanics | ||||||||||
| Controls, n | 303 | 418 | 548 | 917 | 178 | 345 | 594 | 1069 | ||
| Cases, n | 88 | 70 | 75 | 116 | 43 | 91 | 87 | 128 | ||
| aOR4 (95% CI) | ref | 0.58 (0.40, 0.86) | 0.53 (0.36, 0.79) | 0.49 (0.32, 0.76) | 0.002 | ref | 1.30 (0.84, 2.02) | 0.82 (0.53, 1.27) | 0.85 (0.56, 1.29) | 0.04 |
| Other | ||||||||||
| Controls, n | 467 | 359 | 422 | 440 | 394 | 448 | 426 | 420 | ||
| Cases, n | 60 | 54 | 45 | 38 | 63 | 66 | 49 | 19 | ||
| aOR4 (95% CI) | ref | 1.09 (0.71, 1.69) | 0.93 (0.58, 1.50) | 0.78 (0.46, 1.37) | 0.34 | ref | 1.13 (0.76, 1.69) | 1.08 (0.70, 1.65) | 0.64 (0.36, 1.14) | 0.24 |
1
aOR, adjusted OR; DQI, Diet Quality Index; MDS, Mediterranean diet score; NBDPS, National Birth Defects Prevention Study; NH, non-Hispanic; ref, reference.
2
Cochran-Armitage trend test.
3
Logistic regression models adjusted for energy intake (kcal), maternal age, prepregnancy BMI, smoking, and race/ethnicity.
4
Logistic regression models adjusted for energy intake (kcal), maternal age, prepregnancy BMI, and smoking.