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. 2019 May 2;20:329. doi: 10.1186/s12864-019-5689-y

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Analysis of 155 baseline differentially expressed genes between WT and Il10^−/− mice. a Heat map of expression of 155 genes. Annotation of genes is provided in Additional file 2A. b IPA based network analysis of significant (P < 0.05) canonical pathways (Additional file 2C) associated with the 155 genes c LPS/IL-1 Pathway. Genes identified as differentially expressed in Il10^−/− mice are highlighted in pink. The numbers below indicate fold change and p-value. LBP = LPS binding protein; Cyp2b6 = cytochrome P450 2B6; GST = Glutathione S-transferase; ALAS1 = Aminolevulinate synthase 1; CPT = Carnitine Palmitoyltransferase; ACS = Acetyl Coenzyme A synthetase