Table 4.
Comparisons of lipid subclasses amongst the three clusters
Lipid class | Lipid Sub-Class | Fold change | Kruskal-Wallis adjusted p-value |
Tendency | ||
---|---|---|---|---|---|---|
LClus1/LClus3 | LClus2/LClus3 | LClus1/LClus2 | ||||
Acyl carnitines | AcCa | 0.67 | 0.31*** | 2.18 | < 0.0005 | |
Fatty acids | SFA | 0.79 | 1.08*** | 0.73*** | < 0.0005 | Up in LClus2 |
MUFA | 3.59*** | 1.03 | 3.48** | < 0.0005 | Up in LClus1 | |
PUFA | 3.66** | 0.84 | 4.34*** | < 0.0005 | Up in LClus1 | |
Sphingolipids | Cer | 0.54 | 0.81 | 0.66 | 0.117 | |
CerG1 | 1.10 | 0.52*** | 2.11 | < 0.0005 | ||
CerG2 | 8.95* | 4.58 | 1.95** | 0.009 | Up in LClus1 | |
GM3 | 1.00 | 0.23*** | 4.46*** | < 0.0005 | Down in LClus2 | |
SM | 1.37 | 0.49*** | 2.81*** | < 0.0005 | Down in LClus2 | |
So | 1.37 | 0.49* | 2.81 | 0.013 | ||
Neutral lipids | DG | 1.19 | 22.90 | 0.05 | 0.136 | |
TG | 0.82 | 1.23*** | 0.66** | < 0.0005 | Up in LClus2 | |
Phospholipids | PC | 1.85 | 0.40*** | 4.67*** | < 0.0005 | Down in LClus2 |
PE | 2.88 | 0.68*** | 4.27*** | < 0.0005 | Down in LClus2 | |
PG | 0.95 | 0.31*** | 3.09* | < 0.0005 | Down in LClus2 | |
PI | 1.95 | 0.39*** | 4.95*** | < 0.0005 | Down in LClus2 | |
PS | 1.84 | 0.61*** | 3.01* | < 0.0005 | Down in LClus2 | |
LPC | 0.52 | 0.43*** | 1.20 | < 0.0005 | ||
LPE | 0.45 | 0.45*** | 0.99 | < 0.0005 | ||
LPG | 0.79 | 0.31*** | 2.53 | < 0.0005 |
Tendency is indicated only when the cluster is differed from all the other clusters. The * depicts a statistically significant difference. * p < 0.05; ** p < 0.01; *** p < 0.001