Table 3.

CSF marker stratified for presence of cSS.

	Total (n = 101)	CSS (n = 62)	No cSS (n = 39)	P	OR (95% CI)
Aß42 (pg/ml), median (IQR)	474 (352–629)	400 (326–566)	575 (474–730)	0.005	0.2 [0.08–0.7]
Aß40 (pg/ml), median IQR	8,079 (6,803–10,603) (n = 79)	8,170 (7,284–9,534) (n = 44)	7,906 (6,410–13,917) (n = 35)	0.8	0.8 [0.3–2.6]
T-tau (pg/ml), median (IQR)	322 (242–431)	319 (251–436)	331 (216–429)	0.1	1.9 [0.8–4.5]
P-tau (pg/ml), median (IQR)	58 (43–75)	60 (51–86)	50 (36–72)	0.1	2.1 [0.8–5.3]
Aß42/40 ratio, median (IQR)	0.06 (0.04–0.08) (n = 79)	0.05 (0.04–0.07) (n = 44)	0.08 (0.04–0.09) (n = 35)	0.009	0.3 [0.08–0.7]

Logistic regression with adjustment for age, sex, number of cerebral microbleeds, MMSE, cholesterol, diabetes, and hypertension. All CSF marker levels were log-transformed for regression analysis. Odds Ratios correspond to one unit increase in log-transformed levels. Where data were missing; the number of subjects for which data were available is indicated within parentheses. SD, standard deviation; t-tau, total tau; p-tau, phosphorylated tau; Aß42, ß-amyloid 1–42; Aß40, ß-amyloid 1–40; cSS, cortical superficial siderosis; CSF, Cerebrospinal fluid; MMSE, Mini Mental State Examination; OR, odds ratio; CI, confidence interval. Significant values are indicated in bold.