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. 2019 May 2;19:117. doi: 10.1186/s12935-019-0836-8

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — Differentially expressed genes in cell cycle pathway. a Heatmap for differentially expressed genes in any of A, C, D group comparisons. The changed genes by comparison of PC9 and apatinib-treated PC9 cells. b DEGs in cell cycle pathway after treatment of apatinib in PC9GR cells. Only CCKN1C is up regulated and all others are down regulated