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. 2019 May 2;19:117. doi: 10.1186/s12935-019-0836-8

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 8 — Apatinib inhibits the tumor growth of PC9GR cell xenograft in mice. a, b Volume changes of tumors in mice bearing PC9GR and PC9 cells, respectively over 21 days by administration of 100 mg/kg apatinib daily. c Tumor weight changes in mice bearing PC9GR or PC9 cells after treatment where PC9GR tumors shrunk the most. d Photographs of mice in each group and e photographs of tumors in each group. Each group has 6 mice or tumors. Each value represents a group mean ± standard deviation. *p < 0.05, **p < 0.01, ***p < 0.001 compared with the control group using the t test