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. 2019 May 2;19:117. doi: 10.1186/s12935-019-0836-8

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 9 — Effects of apatinib on the expression of pVEGFR2 and CD31 in xenograft models. a Immunohistochemical staining for pVEGFR2 and b CD31 in tumor tissues obtained from the control and apatinib-treated mice. The bar plot value represents the mean ± standard deviation of at least three independent replicates. *p < 0.05, **p < 0.01 compared with control, using the t test