Table 6.
Multivariate logistic regressions of clinical and health related quality of life variables for abnormal categorical liver function variables
| Child’s classes B to C | ALBI grades 2 to 3 | Presence of ascites | MELD grades 2 to 3 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| OR | 95% CI | p-value | OR | 95% CI | p-value | OR | 95% CI | p-value | OR | 95% CI | p-value | |
| EORTC QLQ-C30 Physical Functioning | 0.987 | 0.974–1.000 | 0.045 | 0.973 | 0.961–0.985 | < 0.001 | – | – | – | – | – | – |
| EORTC QLQ-HCC18 Abdominal Swelling | 1.012 | 1.003–1.021 | 0.011 | – | – | – | 1.020 | 1.012–1.028 | < 0.001 | – | – | – |
| CUPI | 4.239 | 2.357–7.626 | < 0.001 | 2.580 | 1.557–4.277 | < 0.001 | 10.538 | 5.944–18.681 | < 0.001 | – | – | – |
| Bilirubin | 1.100 | 1.073–1.126 | < 0.001 | 1.089 | 1.058–1.121 | < 0.001 | 1.010 | 1.001–1.019 | 0.029 | 1.093 | 1.072–1.114 | < 0.001 |
| ln(AFP) | 0.838 | 0.763–0.920 | 0.001 | – | – | – | 0.790 | 0.721–0.865 | < 0.001 | – | – | – |
| Planned treatment modality | – | – | – | 2.149 | 1.162–3.972 | 0.015 | – | – | – | – | – | – |
ALBI albumin-bilirubin, CI Confidence intervals, CUPI the Chinese University Prognostic Index, EORTC European Organization for Research and Treatment of Cancer; ln(AFP) natural logarithm of alpha-feto protein level, MELD Model for End-stage Liver Disease, OR Odds ratio