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. 2019 Feb 12;49(7):1207–1217. doi: 10.1017/S0033291719000199

Table 1.

Demographic and clinical characteristics and performance data of patients with OCD, unaffected first-degree relatives, and unaffected comparison subjects

Patients with OCD Unaffected first-degree relatives of OCD patients Healthy comparison participants Statistic p
Mean s.d. Mean s.d. Mean s.d.
Demographical data
N 117 50 130
Mean age, years 31.9 9.4 45 14.8 32.1 9.9 F(2, 294) = 30.22 0.00
Gender (% female) 53 64 58 χ2(2) = 1.79 0.41
Verbal IQ 103.2 10 106.5 9.6 104.8 9.4 F(2, 294) = 2.17 0.12
Family history
Depressive disorders n in % 45.3 54 21.5 χ2(2) = 30.44 <0.001
SUD n in % 19.7 14 20.8 χ2(2) = 17.70 <0.001
Anxiety disorders n in % 43.6 42 20.8 χ2(2) = 17.70 <0.001
Clinical data
Obsessive-compulsive inventory-revised 27.32 12.17 5.78 6.12 3.85 3.87 F(2,294) = 261.82 <0.001
Beck depression inventory-II 18.81 10.70 3.46 4.38 2.53 3.32 F(2,294) = 169.30 <0.001
State-trait-anxiety-inventory traita 53.12 10.34 33.58 7.52 32.19 7.54 F(2,288) = 191.21 <0.001
Harm avoidant motivation (OC-TCDQ)a 9.92 3.52 2.82 2.18 2.24 1.89 F(2,288) = 271.80 <0.001
Sense of incompleteness (OC-TCDQ)a 15.20 5.40 5.08 3.79 4.39 3.27 F(2,288) = 211.28 <0.001
Yale-brown obsessive-compulsive scaleb 23.27 9.49
Montgomery-Asberg depression rating scaleb 13.23 9.24
Age of onsetb 23.27 9.49
Performance datac
Error rate in % 4.41 3.42 3.44 2.97 4.33 3.26 F(2287) = 0.04 0.97
Reaction time for correct trials 436 48 462 54 438 48 F(2287) = 0.18 0.84
Reaction time for errors 371 76 385 66 373 56
Robust post-error slowing 40 45 52 60 39 47 F(2287) = 0.28 0.76

s.d., standard deviation; OCD, obsessive-compulsive disorder; IQ, intelligence quotient; SUD, substance use disorders; OC-TCDQ, Obsessive-Compulsive Trait Core Dimensions Questionnaire.

a

State-Trait-Anxiety-Inventory and OC-TCDQ scores were missing for six OCD patients.

b

Yale-Brown Obsessive-Compulsive Scale, Montgomery-Asberg Depression Rating Scale and age of onset were only applicable in patients.

c

For performance data, age was included as a covariate to account for group differences. Further, performance data of six participants were missing due to technical problems (n = 2 OCD patients, n = 2 relatives, and n = 2 healthy comparison participants).