Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Apr 26;9:314. doi: 10.3389/fonc.2019.00314

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2019 Nourmohammadi, Aung, Cui, Pei, De Ieso, Harata-Lee, Qu, Adelson and Yool.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Assessment of the effects of CKI and fractions on cell viability and incidence of apoptosis. Viability was measured by Alamar Blue assay in eight cell lines treated with (A) CKI, (B) MN or (C) MJ fractions (at doses present in 2 mg/ml CKI). Cell viability responses standardized as a percentage to mean values for vehicle control were not significantly different (ns) in any condition, based on repeated experiments with 8 replicates total. Apoptosis was compared in three cell lines with and without CKI treatment, for (D) MDA-MB-231, (E) HEK-293, and (F) HFF cells, analyzed by flow cytometry (see Methods for details). Pseudo-color plots illustrate the percentages of cells in the late (quadrant Q2) and early (Q3) stages of apoptosis. (G) Histogram summarizing compiled data (mean ± SD) depicting percentage apoptosis in three cell lines with and without CKI treatment. ****p < 0.0001; ns, not significant.