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. 2019 Apr 26;10:892. doi: 10.3389/fmicb.2019.00892

FIGURE 4.

FIGURE 4

MIC reduction of Pseudomonas spp. of different soil origin after addition of RND EP inhibitor PAβN. Pseudomonas spp. isolates were grown with or without RND EP inhibitor PAβN and their MIC of chloramphenicol was assessed. Blue boxes indicate upper and lower quartiles, whiskers indicate minimum and maximum values excluding outliers, circles depict outliers and crosses indicate mean values. Indicates statistical significance calculated as non-parametric Mann-Whitney test for two independent samples (p < 0.05; one-tailed). (A) Pseudomonas spp. isolates from two farming sites of different style did not show significant differences in MIC reduction after addition of RND EP inhibitor. (B) Pseudomonas spp. with the higher initial resistance to chloramphenicol were more dependent on EP than the isolates with low initial resistance.