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. 2019 Apr 26;10:494. doi: 10.3389/fphys.2019.00494

FIGURE 2.

FIGURE 2

TSF alleviated hepatic steatosis in mice fed a MCDD. (A) Male mice fed a MCDD for 6 weeks and administered TSF (2.4 g/kg/day) by gavage for 4 weeks. (B,C) Body weight was recorded every week, and body weight gain and food intake were measured at the 6th week. (D) Liver triglycerides were measured. (E) Hepatic steatosis and inflammatory cells infiltration (black arrow) in H&E- and Oil Red O-stained sections of mice fed a MCDD treated with or without TSF, bar = 50 μm; CV represents central vein; NAFLD activity score (hepatic steatosis and lobular inflammation) and positive Oil Red O staining area. (F) Serum ALT and AST of mice fed a MCDD treated with or without TSF. Data from each group are expressed as the mean ± SEM (n = 6).aP < 0.05, bP < 0.01 vs. ND group; cP < 0.05, dP < 0.01 vs. MCDD group.