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. 2019 Apr 26;10:877. doi: 10.3389/fimmu.2019.00877

Figure 2.

Figure 2

Resident NK cells displayed an inhibitory profile in the tumor. (A) Resident NK cells (CD45+CD3−CD56+) were identified based on CD103 expression. A representative dot plot of CD103+ and CD103− NK cells gating is shown. Below, a plot chart of CD103+ and CD103− NK cells frequency among all CD56+ cells is shown, where each dot represents one patient (n = 6). (B) Upper panel: Representative graphs of the expression level of Tigit (left panel) or Tim-3 (right panel) in CD103+ NK cells (in red) or CD103− NK cells (in blue). The isotype control was represented in gray. The positive gate was made using the isotype control (>1% of isotype control staining was considered as positive). Lower panel: The expression of Tigit (left panel) and Tim-3 (right panel) among NK cells CD103+ or CD103− was assessed and plotted here. Each dot-line represents one patient n = 6. *p < 0.05, ns: not significant (p > 0.05).