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. 2019 Apr 26;9:333. doi: 10.3389/fonc.2019.00333

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Copyright © 2019 Wang, Meng, Wang, Wen, Jia, Ge, Xie, Hao, Liu and Xu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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e-As₄S₄ down-regulated CD31 in tumor mass. IHC staining of CD31 in tumor tissues of saline (A), soluplus (B), r-As₄S₄ (C), and e-As₄S₄ (D). Scale bar = 50 μm (whole image), scale bar = 20 μm (inserted). (E) IOD of CD31 expression of the four groups **p < 0.01. (F) Western blot analysis of CD31 of tumor tissues lysate. (G) Combined staining of CD31 (red) and α-SMA (green) in tumor tissues. Scale bar = 20 μm.