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. 2019 Apr 23;12:3087–3098. doi: 10.2147/OTT.S200261

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© 2019 Huang et al.

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Knockdown of RARα inhibits Akt signaling. (A) Western blotting to measure the amount of protein pAkt and PCNA in CRC cells. (B) LY294002 treatment decreased the expression of PCNA in RKO and HCT116 lines. (C) Expression of PCNA and Akt in RKO line subjected to various treatments. LY294002, 20 μM.