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. 2019 Apr 5;10(27):2644–2656. doi: 10.18632/oncotarget.26804

Figure 1. miRNA expression pattern in N1 and N0 PDAC samples.

Figure 1

(A) Affymetrix microarray hierarchical clustering performed on miRNA of LN positive (N1) compared to LN negative (N0) PDAC samples (p<0.05). A colored bar indicating the standardized log2 intensities accompanies the expression profile. (B) qRT-PCR validation of the expression levels of three representative up regulated miRNA: hsa-miR-125-b*, hsa-miR-196a, hsa-miR-155. (C) qRT-PCR validation of the expression levels of four representative down regulated miRNA: hsa-miR-720, hsa-miR-130b, hsa-miR-216a and hsa-miR-141 from the indicated groups: Normal, N0 and N1. Each histogram represents the average of 8 samples as indicated in materials and methods (n=8). *P <0.05; **P < 0.01; ***P <.0001.