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. 2019 Apr 26;10:383. doi: 10.3389/fphar.2019.00383

Table 2.

Optimal parameters and performance per CMA method, based on 100 simulations of 1000 individuals.

CMA9 LCMA1 LCMA1-thr LCMA2 LCMA2-thr
Window size 150 60 90 60
Overlap 80% 70% 0% 0%
Mean cARI [95% CI] 0.35 [0.33–0.36] 0.65 [0.62–0.68] 0.65 [0.62–0.68] 0.72 [0.69–0.74] 0.58 [0.55–0.62]
Classification accuracy [95% CI]
Consistent adherence 100% 100% 100% 100% 100%
[100–100%] [100–100%] [100–100%] [100–100%] [100–100%]
Erratic adherence 18% 29% 27% 33% 29%
[13–23%] [23–35%] [21–34%] [28–39%] [23–35%]
Gradual decline 53% 74% 65% 85% 77%
[45–62%] [66–82%] [57–74%] [77–91%] [70–85%]
Intermittent adherence 51% 70% 75% 76% 74%
[43–60%] [62–77%] [68–83%] [69–83%] [67–81%]
Partial drop-offs 51% 81% 84% 86% 89%
[43–59%] [75–88%] [77–90%] [80–92%] [85–95%]
Non-persistence 100% 100% 89% 100% 21%
[100–100%] [100–100%] [84–95%] [100–100%] [14–28%]
Overall 66% 80% 79% 84% 75%
[65–68%] [79–82%] [78–81%] [83–86%] [73–76%]

A classification accuracy of 100% indicates that the clustering algorithm correctly identified all individuals of a pre-allocated group. cARI: adjusted Rand Index for all groups, CI: confidence interval.